12.07.2011 -
A test strip for the quick measurement of total bilirubin
in the blood, even outside a hospital environment. Bilirubin plays
a major role in neonatal jaundice and can potentially damage the
central nervous system due to its ability to pass through the
blood-brain barrier.
It is for this project that the young Argentine
researcher, Carlos Coda Zabetta, representing the Innovation
Factory "Bilistick" development group, the start-up incubator of
Trieste AREA Science Park, received one of the €30,000 prizes
awarded by Working Capital-PNI - the initiative of Telecom Italia
and PNICube (Association of Italian University Incubators) that
supports young talent in the field of Italian innovation and
promotes the creation of start-ups.
The new, first level quick diagnostic system (with a
patent pending) is particularly suitable for use in screening
projects in developing countries or in isolated parts of the
northern hemisphere. Here, monitoring in the first few days
following childbirth is necessary for non-Caucasians, whose skin
colour means that the onset of jaundice, resulting from abnormal
levels of free bilirubin, is difficult to spot.
In many of these countries, due to the lack of healthcare
facilities and the way the population is distributed across the
territory, it becomes crucial for qualified health care
professionals (professional nurses/laboratory technicians),
although not necessarily medical professionals, to be able to
operate beyond the Point of Care.
In addition, since there are currently no test strip
systems on the market capable of performing the type of analysis
carried out by Bilistick, there is also a potential market in
developed countries. Here, bilirubin levels are measured in
laboratories with a several hour wait for results and there are
cases where suspected abnormal levels are sometimes subject to
unnecessary treatment at an estimated cost of $500-$600 per
patient.
The team
The idea was born thanks to the inspiration of Dr Richard
Partridge Wennberg from the University of Washington, Professor
Claudio Tiribelli, Director and Cristina Bellarosa, Deputy Director
of the Fondazione Italiana Fegato-ONLUS (Foundation for the Study
of Liver Diseases - non-profit organisation).
Together with Innovation Factory, the AREA Science Park
incubator, they created the "Bilistick" development group. The
Consorzio di Biomedicina Molecolare in Trieste (Consortium for
Molecular Biomedicine), Microlab srl in Padua and the University of
Trieste have also since joined the team.